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Meet Rick, living with hereditary transthyretin-mediated (hATTR) amyloidosis. When Rick’s symptoms began to pile up, he thought it might have been due to old age. However, Rick reached his tipping point when his symptoms got worse. His brother recommended that Rick get tested for hATTR amyloidosis, which led to the right diagnosis.

Hereditary ATTR (hATTR) amyloidosis is a rare, inherited, rapidly progressive disease caused by variants, or changes, in the transthyretin, or TTR, gene. These variants cause the TTR protein to take on an abnormal shape and build up as amyloid deposits in various parts of the body, including the nerves, heart, and digestive system, which cause