Stephen J. Russell, MD, PhD

Dr. Stephen J. Russell is a Hematologist/Internist at Mayo Clinic, Rochester, Minnesota. His areas of interests are multiple myeloma, dysproteinemias, gene therapy, virus therapy, and amyloidosis. He completed his PhD from University of London and fellowship in FRCP from Royal College of Physicians of the United Kingdom.

The research interests of Stephen J. Russell center on demonstrating the value of oncolytic virotherapy as a new modality for the treatment of cancer. Viruses from several families are engineered in Dr. Russell’s laboratory. His team currently has oncolytic projects focusing on measles, vesicular stomatitis virus (VSV), coxsackievirus A21 (CVA21) and Mengo virus. Nonreplicative adeno-associated viruses, lentivirus and adenovirus vectors also are used extensively.

Representative Publications:

Optimizing deep response assessment for AL amyloidosis using involved free light chain level at end of therapy: failure of the serum free light chain ratio

Absolute values of immunoglobulin free light chains are prognostic in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation

Prognostic value of minimal residual disease and polyclonal plasma cells in myeloma patients achieving a complete response to therapy 

Impact of prior diagnosis of monoclonal gammopathy on outcomes in newly diagnosed multiple myeloma 

Peripheral blood biomarkers of early immune reconstitution in newly diagnosed multiple myeloma