Matthew Wheeler, MD, PhD

Matthew Wheeler is an Assistant Professor of Medicine (Cardiovascular Medicine) at the Stanford University Medical Center. He is also an Adult Medical Director and Executive Director at Stanford Center of Undiagnosed Diseases. He graduated from University of Chicago Pritzker School of Medicine and has been in practice for 12 years. He completed his residency at Stanford University. He specializes in Internal Medicine.

is physician scientist with interests in cardiomyopathies, rare and undiagnosed diseases, therapeutics and genomics. He is a physician with interest and experience treating patients with hypertrophic cardiomyopathy and other inherited cardiomyopathies. Dr. Wheeler has made extensive translational science efforts, participating in several ongoing clinical trials for hypertrophic cardiomyopathy, dilated cardiomyopathy, ATTR cardiac amyloidosis, and mechanical circulatory support.

Dr. Wheeler is a co-investigator of the Bioinformatics Center of the Molecular Transducers of Physical Activity Consortium. He pursue projects and collaborations at the intersection of striated muscle genetics, genomics, and clinical investigation.

Representative Publications:

Angiotensin-Converting Enzyme Genotype Predicts Cardiac and Autonomic Responses to Prolonged Exercise
Cardiomyopathy in Animal Models of Muscular Dystrophy
Cardiomyopathy is Independent of Skeletal Muscle Disease in Muscular Dystrophy
Secondary Coronary Artery Vasospasm Promotes Cardiomyopathy Progression
Smooth Muscle Cell-Extrinsic Vascular Spasm Arises From Cardiomyocyte Degeneration in Sarcoglycan-Deficient Cardiomyopathy